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Target5-hydroxytryptamine receptor 1D
LigandBDBM50049084
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1997 (CHEMBL617599)
Ki 16±n/a nM
Citation Glennon, RAHong, SSBondarev, MLaw, HDukat, MRakhi, SPower, PFan, EKinneau, DKamboj, RTeitler, MHerrick-Davis, KSmith, C Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors. J Med Chem39:314-22 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D
Name:5-hydroxytryptamine receptor 1D
Synonyms:5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41920.63
Organism:Homo sapiens (Human)
Description:Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50049084
n/a
NameBDBM50049084
Synonyms:2-[5-(7,7-Dimethyl-octyloxy)-1H-indol-3-yl]-ethylamine | CHEMBL111150
TypeSmall organic molecule
Emp. Form.C20H32N2O
Mol. Mass.316.4809
SMILESCC(C)(C)CCCCCCOc1ccc2[nH]cc(CCN)c2c1
Structure
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