| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
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| Ligand | BDBM50049100 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2026 (CHEMBL617321) |
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| Ki | 10±n/a nM |
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| Citation |  Glennon, RA; Hong, SS; Bondarev, M; Law, H; Dukat, M; Rakhi, S; Power, P; Fan, E; Kinneau, D; Kamboj, R; Teitler, M; Herrick-Davis, K; Smith, C Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors. J Med Chem39:314-22 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1B |
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| Name: | 5-hydroxytryptamine receptor 1B |
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| Synonyms: | 5-HT-1B | 5-HT-1D-beta | 5-HT1B | 5-hydroxytryptamine receptor 1B (5-HT1B) | 5HT1B_HUMAN | HTR1B | HTR1DB | S12 | Serotonin (5-HT) receptor | Serotonin 1D beta receptor | Serotonin Receptor 1B |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43579.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells |
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| Residue: | 390 |
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| Sequence: | MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
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| BDBM50049100 |
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| n/a |
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| Name | BDBM50049100 |
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| Synonyms: | 6-Amino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxylic acid amide | CHEMBL111316 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15N3O |
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| Mol. Mass. | 229.2777 |
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| SMILES | NC1CCc2[nH]c3ccc(cc3c2C1)C(N)=O |
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| Structure | 
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