| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
|---|
| Ligand | BDBM28699 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_153485 (CHEMBL761650) |
|---|
| EC50 | 51000±n/a nM |
|---|
| Citation |  Willson, TM; Cobb, JE; Cowan, DJ; Wiethe, RW; Correa, ID; Prakash, SR; Beck, KD; Moore, LB; Kliewer, SA; Lehmann, JM The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem39:665-8 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor alpha |
|---|
| Name: | Peroxisome proliferator-activated receptor alpha |
|---|
| Synonyms: | Nr1c1 | Nuclear receptor subfamily 1 group C member 1 | PPAR-alpha | PPARA_MOUSE | Peroxisome Proliferator-Activated Receptor alpha | Ppar | Ppara |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 52343.28 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_572395 |
|---|
| Residue: | 468 |
|---|
| Sequence: | MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSIGEESSGSFGFADYQYLGSC
PGSEGSVITDTLSPASSPSSVSCPVIPASTDESPGSALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDLKDSETADLKSLGKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFV
IHDMETLCMAEKTLVAKMVANGVEDKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKLQEGIVHVLKLHLQSNHPDDT
FLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY
|
|
|
|---|
| BDBM28699 |
|---|
| n/a |
|---|
| Name | BDBM28699 |
|---|
| Synonyms: | 2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMBL683 | Clofibrate | Clofibrinic acid | clofibric acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H11ClO3 |
|---|
| Mol. Mass. | 214.646 |
|---|
| SMILES | CC(C)(Oc1ccc(Cl)cc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
