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TargetPeroxisome proliferator-activated receptor gamma
LigandBDBM50049247
Substrate/Competitorn/a
Meas. Tech.ChEMBL_154537
EC50 10000±n/a nM
Citation Willson TMCobb JECowan DJWiethe RWCorrea IDPrakash SRBeck KDMoore LBKliewer SALehmann JM The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 39:665-8 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peroxisome proliferator-activated receptor gamma
Name:Peroxisome proliferator-activated receptor gamma
Synonyms:Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma
Type:PROTEIN
Mol. Mass.:57593.55
Organism:Mus musculus
Description:ChEMBL_1453700
Residue:505
Sequence:
MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQL
LHVIKKTETDMSLHPLLQEIYKDLY
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  Blast E-value cutoff:
BDBM50049247
n/a
NameBDBM50049247
Synonyms:5-{4-[2-(Benzooxazol-2-yl-methyl-amino)-ethoxy]-phenyl}-thiazolidine-2,4-dione | CHEMBL129562
TypeSmall organic molecule
Emp. Form.C19H17N3O4S
Mol. Mass.383.421
SMILESCN(CCOc1ccc(cc1)-c1sc(=O)[nH]c1O)c1nc2ccccc2o1
Structure
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