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TargetMu-type opioid receptor
LigandBDBM50049804
Substrate/Competitorn/a
Meas. Tech.ChEMBL_145152 (CHEMBL755956)
Ki>100±n/a nM
Citation Cappelli, AAnzini, MVomero, SMenziani, MCDe Benedetti, PGSbacchi, MClarke, GDMennuni, L Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors. J Med Chem39:860-72 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:Enzyme Catalytic Domain
Mol. Mass.:11165.58
Organism:GUINEA PIG
Description:P97266
Residue:98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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BDBM50049804
n/a
NameBDBM50049804
Synonyms:1H-Indole-2-carboxylic acid [2-(7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide | CHEMBL127619
TypeSmall organic molecule
Emp. Form.C27H25ClN4O
Mol. Mass.456.967
SMILESCN1C(CCNC(=O)c2cc3ccccc3[nH]2)CN=C(c2ccccc2)c2cc(Cl)ccc12 |t:20|
Structure
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