| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM22916 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_83829 (CHEMBL692770) |
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| Ki | 5±n/a nM |
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| Citation |  Stark, H; Purand, K; Hüls, A; Ligneau, X; Garbarg, M; Schwartz, JC; Schunack, W [125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor. J Med Chem39:1220-6 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM22916 |
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| n/a |
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| Name | BDBM22916 |
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| Synonyms: | 5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole | CHEMBL19010 | Iodoproxyfan |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15IN2O |
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| Mol. Mass. | 342.1755 |
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| SMILES | Ic1ccc(COCCCc2cnc[nH]2)cc1 |
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| Structure | 
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