| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50050487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146694 (CHEMBL753771) |
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| Ki | 25.2±n/a nM |
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| Citation |  Schultz, AG; Wang, A; Alva, C; Sebastian, A; Glick, SD; Deecher, DC; Bidlack, JM Asymmetric syntheses, opioid receptor affinities, and antinociceptive effects of 8-amino-5,9-methanobenzocyclooctenes, a new class of structural analogues of the morphine alkaloids. J Med Chem39:1956-66 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45038.37 |
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| Organism: | CALF |
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| Description: | OPIATE Mu 2 0 CALF::P79350 |
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| Residue: | 401 |
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| Sequence: | MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLC
PSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALA
TSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALD
LRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVF
IFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIH
IYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSST
IEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
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| BDBM50050487 |
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| n/a |
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| Name | BDBM50050487 |
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| Synonyms: | 10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0*2,7*]trideca-2,4,6-trien-4-ol | CHEMBL431947 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H27NO2 |
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| Mol. Mass. | 289.4125 |
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| SMILES | COCC12Cc3ccc(O)cc3C(C)(CCC1N(C)C)C2 |THB:17:16:20:11.5.4,10:11:20:16.15.14| |
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| Structure | 
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