| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM50050947 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_216403 (CHEMBL820116) |
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| IC50 | 2000±n/a nM |
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| Citation |  Higgins, JD; Bridger, GJ; Derian, CK; Beblavy, MJ; Hernandez, PE; Gaul, FE; Abrams, MJ; Pike, MC; Solomon, HF N-terminus urea-substituted chemotactic peptides: new potent agonists and antagonists toward the neutrophil fMLF receptor. J Med Chem39:1013-5 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM50050947 |
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| n/a |
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| Name | BDBM50050947 |
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| Synonyms: | (S)-2-{(S)-2-[(S)-2-(3-Isopropyl-ureido)-4-methylsulfanyl-butyrylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid | CHEMBL7034 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H38N4O5S |
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| Mol. Mass. | 494.647 |
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| SMILES | CSCC[C@H](NC(=O)NC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
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| Structure | 
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