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TargetRibonucleoside-diphosphate reductase subunit M2
LigandBDBM50051769
Substrate/Competitorn/a
Meas. Tech.ChEMBL_195255
IC50 1300±n/a nM
Citation Liu MCLin TSCory JGCory AHSartorelli AC Synthesis and biological activity of 3- and 5-amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone. J Med Chem 39:2586-93 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Ribonucleoside-diphosphate reductase subunit M2
Name:Ribonucleoside-diphosphate reductase subunit M2
Synonyms:RR2 | RRM2 | Ribonucleoside-diphosphate reductase M2 chain | Ribonucleotide reductase small chain | Ribonucleotide reductase small subunit
Type:PROTEIN
Mol. Mass.:44868.59
Organism:Homo sapiens (Human)
Description:ChEMBL_195255
Residue:389
Sequence:
MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKT
KAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLK
PEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLI
DTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF
ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIE
QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTN
FFEKRVGEYQRMGVMSSPTENSFTLDADF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50051769
n/a
NameBDBM50051769
Synonyms:(1Z,N'E)-N'-((5-(methylamino)pyridin-2-yl)methylene)carbamohydrazonothioic acid | CHEMBL314693
TypeSmall organic molecule
Emp. Form.C8H11N5S
Mol. Mass.209.271
SMILESCNc1ccc(C=NNC(N)=S)nc1 |w:6.5|
Structure
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