| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ribonucleoside-diphosphate reductase subunit M2 |
|---|
| Ligand | BDBM50051767 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_195255 (CHEMBL796773) |
|---|
| IC50 | 1400±n/a nM |
|---|
| Citation |  Liu, MC; Lin, TS; Cory, JG; Cory, AH; Sartorelli, AC Synthesis and biological activity of 3- and 5-amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone. J Med Chem39:2586-93 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ribonucleoside-diphosphate reductase subunit M2 |
|---|
| Name: | Ribonucleoside-diphosphate reductase subunit M2 |
|---|
| Synonyms: | RIR2_HUMAN | RR2 | RRM2 | Ribonucleoside-diphosphate reductase M2 chain | Ribonucleotide reductase small chain | Ribonucleotide reductase small subunit |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44868.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_195255 |
|---|
| Residue: | 389 |
|---|
| Sequence: | MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKT
KAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLK
PEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLI
DTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF
ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIE
QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTN
FFEKRVGEYQRMGVMSSPTENSFTLDADF
|
|
|
|---|
| BDBM50051767 |
|---|
| n/a |
|---|
| Name | BDBM50051767 |
|---|
| Synonyms: | (1Z,N'E)-N'-((5-(propylamino)pyridin-2-yl)methylene)carbamohydrazonothioic acid | CHEMBL86963 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H15N5S |
|---|
| Mol. Mass. | 237.325 |
|---|
| SMILES | CCCNc1ccc(C=NNC(N)=S)nc1 |w:8.7| |
|---|
| Structure | 
|
|---|
Search and Browse
