| Reaction Details |
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 | Report a problem with these data |
| Target | E-selectin |
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| Ligand | BDBM50051835 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60881 (CHEMBL673528) |
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| IC50 | 1000000±n/a nM |
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| Citation |  Ramphal, JY; Hiroshige, M; Lou, B; Gaudino, JJ; Hayashi, M; Chen, SM; Chiang, LC; Gaeta, FC; DeFrees, SA Ligand interactions with E-selectin. Identification of a new binding site for recognition of N-acyl aromatic glucosamine substituents of sialyl Lewis X. J Med Chem39:1357-60 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| E-selectin |
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| Name: | E-selectin |
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| Synonyms: | ELAM1 | LYAM2_HUMAN | SELE | Selectin | Selectin E |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66642.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1438995 |
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| Residue: | 610 |
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| Sequence: | MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL
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| BDBM50051835 |
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| n/a |
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| Name | BDBM50051835 |
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| Synonyms: | CHEMBL2368520 | Ethyl(Sodium 5-actamido-3,5-dideoxy-alpha-D-glycero-D-galacto-nonulopyronosylonate)-(2,3)-O-(beta-D-galactopyranosyl)-(1,4)-O(alpha-L-fucopyranosyl)-(1,3)-O-[2-(N-acetylamido)-2-deoxy-beta-D-glucopyranosyl]-(1,3)-O-beta-D-galactopyranoside(N-acetyl SLex) |
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| Type | Small organic molecule |
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| Emp. Form. | C39H65N2NaO28 |
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| Mol. Mass. | 1032.9198 |
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| SMILES | [Na+].[H][C@]1(O[C@@](C[C@@H](O)[C@H]1NC(C)=O)(O[C@H]1[C@@H](O)[C@H](CO)O[C@@H](O[C@@H]2[C@H](CO)O[C@@H](O[C@H]3[C@@H](O)[C@H](CO)O[C@@H](OCC)[C@H]3O)[C@@H](NC(C)=O)[C@H]2O[C@@H]2O[C@@H](C)[C@@H](O)[C@H](O)[C@@H]2O)[C@H]1O)C([O-])=O)[C@H](O)[C@H](O)CO |
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| Structure | 
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