| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50052195 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60660 (CHEMBL671697) |
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| Ki | 1.5±n/a nM |
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| Citation |  Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Dopamine D3 and D4 receptor antagonists: synthesis and structure--activity relationships of (S)-(+)-N-(1-Benzyl-3-pyrrolidinyl)-5-chloro-4- [(cyclopropylcarbonyl) amino]-2-methoxybenzamide (YM-43611) and related compounds. J Med Chem39:2764-72 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50052195 |
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| n/a |
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| Name | BDBM50052195 |
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| Synonyms: | CHEMBL93198 | N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-propionylamino-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26ClN3O3 |
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| Mol. Mass. | 415.913 |
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| SMILES | CCC(=O)Nc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)C1 |
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| Structure | 
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