| Reaction Details |
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 | Report a problem with these data |
| Target | B2 bradykinin receptor |
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| Ligand | BDBM50052512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_40421 (CHEMBL652636) |
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| Ki | 0.57±n/a nM |
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| Citation |  Mavunkel, BJ; Lu, Z; Goehring, RR; Lu, S; Chakravarty, S; Perumattam, J; Novotny, EA; Connolly, M; Valentine, H; Kyle, DJ Synthesis and characterization of pseudopeptide bradykinin B2 receptor antagonists containing the 1,3,8-triazaspiro[4.5]decan-4-one ring system. J Med Chem39:3169-73 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B2 bradykinin receptor |
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| Name: | B2 bradykinin receptor |
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| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44467.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
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| Residue: | 391 |
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| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
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| BDBM50052512 |
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| n/a |
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| Name | BDBM50052512 |
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| Synonyms: | 1-Cyclohexyl-8-methyl-3-(2-oxo-propyl)-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL110188 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H29N3O2 |
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| Mol. Mass. | 307.4311 |
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| SMILES | CN1CCC2(CC1)N(CN(CC(C)=O)C2=O)C1CCCCC1 |
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| Structure | 
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