| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50052925 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_215007 (CHEMBL818806) |
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| IC50 | 14±n/a nM |
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| Citation |  Ogawa, H; Yamashita, H; Kondo, K; Yamamura, Y; Miyamoto, H; Kan, K; Kitano, K; Tanaka, M; Nakaya, K; Nakamura, S; Mori, T; Tominaga, M; Yabuuchi, Y Orally active, nonpeptide vasopressin V2 receptor antagonists: a novel series of 1-[4-(benzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepines and related compounds. J Med Chem39:3547-55 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 40761.85 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | n/a |
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| Residue: | 371 |
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| Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
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| BDBM50052925 |
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| n/a |
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| Name | BDBM50052925 |
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| Synonyms: | CHEMBL331098 | N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-3-methyl-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C27H29N3O2 |
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| Mol. Mass. | 427.5381 |
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| SMILES | CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3cccc(C)c3)cc2)c2ccccc12 |
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| Structure | 
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