| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-alpha |
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| Ligand | BDBM50031460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_196783 (CHEMBL799727) |
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| IC50 | >2000±n/a nM |
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| Citation |  Muccio, DD; Brouillette, WJ; Alam, M; Vaezi, MF; Sani, BP; Venepally, P; Reddy, L; Li, E; Norris, AW; Simpson-Herren, L; Hill, DL Conformationally defined 6-s-trans-retinoic acid analogs. 3. Structure-activity relationships for nuclear receptor binding, transcriptional activity, and cancer chemopreventive activity. J Med Chem39:3625-35 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-alpha |
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| Name: | Retinoic acid receptor RXR-alpha |
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| Synonyms: | Nr2b1 | RXRA_MOUSE | Retinoid X receptor alpha | Rxra |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51225.80 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_196493 |
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| Residue: | 467 |
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| Sequence: | MDTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIGSPLGSPGQLHSPISTLS
SPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNG
VLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNK
DCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKI
LEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLD
DQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVS
KMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRF
AKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT
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| BDBM50031460 |
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| n/a |
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| Name | BDBM50031460 |
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| Synonyms: | (2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid | CHEMBL46398 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H30O2 |
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| Mol. Mass. | 314.4617 |
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| SMILES | CCC1=C(C(C)C)\C(CCC1)=C\C(\C)=C\C=C\C(\C)=C\C(O)=O |c:2| |
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| Structure | 
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