| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2 |
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| Ligand | BDBM50053136 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_156184 (CHEMBL760953) |
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| IC50 | 1.4±n/a nM |
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| Citation |  Hagishita, S; Yamada, M; Shirahase, K; Okada, T; Murakami, Y; Ito, Y; Matsuura, T; Wada, M; Kato, T; Ueno, M; Chikazawa, Y; Yamada, K; Ono, T; Teshirogi, I; Ohtani, M Potent inhibitors of secretory phospholipase A2: synthesis and inhibitory activities of indolizine and indene derivatives. J Med Chem39:3636-58 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2 |
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| Name: | Phospholipase A2 |
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| Synonyms: | Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor |
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| Type: | Protein |
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| Mol. Mass.: | 16364.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04054 |
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| Residue: | 148 |
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| Sequence: | MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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| BDBM50053136 |
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| n/a |
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| Name | BDBM50053136 |
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| Synonyms: | (1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indolizin-8-yloxy)-acetic acid methyl ester | CHEMBL121627 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H24N2O5 |
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| Mol. Mass. | 456.4899 |
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| SMILES | COC(=O)COc1cccn2c(Cc3ccccc3-c3ccccc3)c(C)c(C(=O)C(N)=O)c12 |
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| Structure | 
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