| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1 |
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| Ligand | BDBM50053356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_99831 (CHEMBL709861) |
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| Ki | 2.8±n/a nM |
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| Citation |  Daines, RA; Chambers, PA; Foley, JJ; Griswold, DE; Kingsbury, WD; Martin, LD; Schmidt, DB; Sham, KK; Sarau, HM (E)-3-[6-[[(2,6-dichlorophenyl)thio]methyl]-3-(2-phenylethoxy)-2- pyridinyl]-2-propenoic acid: a high-affinity leukotriene B4 receptor antagonist with oral antiinflammatory activity. J Med Chem39:3837-41 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene B4 receptor 1 |
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| Name: | Leukotriene B4 receptor 1 |
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| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37582.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15722 |
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| Residue: | 352 |
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| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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| BDBM50053356 |
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| n/a |
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| Name | BDBM50053356 |
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| Synonyms: | (E)-3-{3-[4-(4-Methoxy-phenyl)-butoxy]-6-phenylsulfanylmethyl-pyridin-2-yl}-acrylic acid | CHEMBL123862 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27NO4S |
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| Mol. Mass. | 449.562 |
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| SMILES | COc1ccc(CCCCOc2ccc(CSc3ccccc3)nc2\C=C\C(O)=O)cc1 |
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| Structure | 
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