| Reaction Details |
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 | Report a problem with these data |
| Target | Calpain-2 catalytic subunit |
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| Ligand | BDBM50053866 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_43853 (CHEMBL658514) |
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| Ki | 300±n/a nM |
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| Citation |  Li, Z; Ortega-Vilain, AC; Patil, GS; Chu, DL; Foreman, JE; Eveleth, DD; Powers, JC Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases. J Med Chem39:4089-98 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calpain-2 catalytic subunit |
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| Name: | Calpain-2 catalytic subunit |
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| Synonyms: | CAN2_HUMAN | CANP 2 | CANPL2 | CAPN2 | Calcium-activated neutral proteinase 2 | Calpain 2 | Calpain M-type | Calpain large polypeptide L2 | Calpain-2 (m-Calpain) | Calpain-2 catalytic subunit | Calpain-2 large subunit | Calpain1/2 | M-calpain | Millimolar-calpain | calpain |
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| Type: | Protein |
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| Mol. Mass.: | 79965.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 700 |
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| Sequence: | MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF
KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI
LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC
SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN
CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK
MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPG
EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFD
NFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL
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| BDBM50053866 |
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| n/a |
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| Name | BDBM50053866 |
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| Synonyms: | CHEMBL131707 | Quinoline-2-carboxylic acid [1-(1-ethylaminooxalyl-propylcarbamoyl)-3-methyl-butyl]-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C23H30N4O4 |
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| Mol. Mass. | 426.5087 |
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| SMILES | CCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)c1ccc2ccccc2n1 |
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| Structure | 
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