| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM50053800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_47385 |
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| Ki | 0.14±n/a nM |
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| Citation |  Li Z; Ortega-Vilain AC; Patil GS; Chu DL; Foreman JE; Eveleth DD; Powers JC Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases. J Med Chem 39:4089-98 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | BCSB | Cathepsin B precursor | Cathepsin B1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 36657.87 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Bovine spleen CB was purchased from Sigma Co. (USA). |
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| Residue: | 335 |
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| Sequence: | MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCG
AILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSW
NTDWGDNGFFKILRGQDHCGIESEIVAGMPCTHQY
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| BDBM50053800 |
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| n/a |
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| Name | BDBM50053800 |
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| Synonyms: | (1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-2H-quinolin-1-yl)-propylcarbamoyl]-ethylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester | CHEMBL132611 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H46N4O5 |
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| Mol. Mass. | 614.7742 |
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| SMILES | CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCCN1CCCC2C=CC=CC12 |c:42,44| |
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| Structure | 
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