| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Genome polyprotein |
|---|
| Ligand | BDBM50055218 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_393 (CHEMBL615643) |
|---|
| Ki | 4±n/a nM |
|---|
| Citation |  Webber, SE; Tikhe, J; Worland, ST; Fuhrman, SA; Hendrickson, TF; Matthews, DA; Love, RA; Patick, AK; Meador, JW; Ferre, RA; Brown, EL; DeLisle, DM; Ford, CE; Binford, SL Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease. J Med Chem39:5072-82 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Genome polyprotein |
|---|
| Name: | Genome polyprotein |
|---|
| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44361.04 |
|---|
| Organism: | Human rhinovirus B |
|---|
| Description: | ChEMBL_158953 |
|---|
| Residue: | 401 |
|---|
| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
|
|
|
|---|
| BDBM50055218 |
|---|
| n/a |
|---|
| Name | BDBM50055218 |
|---|
| Synonyms: | 1-(2-naphthlmethyl) isatin-5-carboxamide | 1-Naphthalen-2-ylmethyl-2,3-dioxo-2,3-dihydro-1H-indole-5-carboxylic acid amide | CHEMBL358279 | acs.jmedchem.1c00409_ST.74 | med.21724, Compound 108 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H14N2O3 |
|---|
| Mol. Mass. | 330.3368 |
|---|
| SMILES | NC(=O)c1ccc2N(Cc3ccc4ccccc4c3)C(=O)C(=O)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
