| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2, major isoenzyme |
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| Ligand | BDBM50055371 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_156352 (CHEMBL761682) |
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| IC50 | 97±n/a nM |
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| Citation |  Draheim, SE; Bach, NJ; Dillard, RD; Berry, DR; Carlson, DG; Chirgadze, NY; Clawson, DK; Hartley, LW; Johnson, LM; Jones, ND; McKinney, ER; Mihelich, ED; Olkowski, JL; Schevitz, RW; Smith, AC; Snyder, DW; Sommers, CD; Wery, JP Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides. J Med Chem39:5159-75 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2, major isoenzyme |
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| Name: | Phospholipase A2, major isoenzyme |
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| Synonyms: | Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 |
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| Type: | Hydrolase; monomer or homodimer |
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| Mol. Mass.: | 16279.83 |
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| Organism: | Sus scrofa (pig) |
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| Description: | Purchased from Sigma. |
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| Residue: | 146 |
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| Sequence: | MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPV
DELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNC
DRNAAICFSKAPYNKEHKNLDTKKYC
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| BDBM50055371 |
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| n/a |
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| Name | BDBM50055371 |
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| Synonyms: | (3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-indol-4-yloxy)-acetic acid | CHEMBL357979 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H22N2O5 |
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| Mol. Mass. | 442.4633 |
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| SMILES | Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1-c1ccccc1 |
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| Structure | 
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