| Reaction Details |
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 | Report a problem with these data |
| Target | 5-lipoxygenase |
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| Ligand | BDBM50041807 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157767 (CHEMBL767670) |
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| IC50 | >30000±n/a nM |
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| Citation |  Müller, K; Prinz, H Antipsoriatic anthrones with modulated redox properties. 4. Synthesis and biological activity of novel 9,10-dihydro-1,8-dihydroxy-9-oxo-2-anthracenecarboxylic and -hydroxamic acids. J Med Chem40:2780-7 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-lipoxygenase |
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| Name: | 5-lipoxygenase |
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| Synonyms: | Arachidonate 5-lipoxygenase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49994.23 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_157766 |
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| Residue: | 430 |
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| Sequence: | MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE
ELGDIQLIKIEKRKYWFHDDWYLKYITVKTPCGDYIEFPCYRWISGEGEIVLRDGQAKLA
CDDQIHVLKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSKAMENLFINRFMHMFQSSWSDFADFEKIFVRISNTISERVMNHWQEDRMFGYQFLNG
CNPVMIQRCLKLPDNLPVTTEMVECSLERQLTLEQEIEQGNIFIVDFKLLDGIDANKTDP
CTLQFLAAPICLLYKNLANKIVPIAIQLNQVPGEENPIFLPSDAKYDWLLAKIWVRSSDF
HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEYG
LFDKANATGG
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| BDBM50041807 |
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| n/a |
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| Name | BDBM50041807 |
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| Synonyms: | 4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-ylmethyl)-benzoic acid methyl ester | CHEMBL44843 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H18O5 |
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| Mol. Mass. | 374.386 |
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| SMILES | COC(=O)c1ccc(Cc2ccc3Cc4cccc(O)c4C(=O)c3c2O)cc1 |
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| Structure | 
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