| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 1 |
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| Ligand | BDBM50004863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105574 (CHEMBL709771) |
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| EC50 | >300000±n/a nM |
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| Citation |  Acher, FC; Tellier, FJ; Azerad, R; Brabet, IN; Fagni, L; Pin, JP Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes. J Med Chem40:3119-29 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 1 |
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| Name: | Metabotropic glutamate receptor 1 |
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| Synonyms: | GPRC1A | GRM1 | GRM1_HUMAN | MGLUR1 | Metabotropic Glutamate 1a | metabotropic glutamate 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 132358.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13255 |
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| Residue: | 1194 |
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| Sequence: | MVGLLLFFFPAIFLEVSLLPRSPGRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAE
KVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSI
EFIRDSLISIRDEKDGINRCLPDGQSLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDI
PQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESG
MDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLL
SAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLD
TNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRICTGNESLEENYVQDSKMGFVINAIYAM
AHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSSFIGVSGEEVWFDEKGDAPGRYD
IMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGE
VSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFS
CLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQ
RLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTL
VVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPAN
FNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIA
KPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKAGAGNANSNGKSVSWSEPGG
GQVPKGQHMWHRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDTSTKTLYNVEEE
EDAQPIRFSPPGSPSMVVHRRVPSAATTPPLPSHLTAEETPLFLAEPALPKGLPPPLQQQ
QQPPPQQKSLMDQLQGVVSNFSTAIPDFHAVLAGPGGPGNGLRSLYPPPPPPQHLQMLPL
QLSTFGEELVSPPADDDDDSERFKLLQEYVYEHEREGNTEEDELEEEEEDLQAASKLTPD
DSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVSYASVILRDYKQSSSTL
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| BDBM50004863 |
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| n/a |
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| Name | BDBM50004863 |
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| Synonyms: | (+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid | (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid | 1-Amino-cyclopentane-1,3-dicarboxylic acid (APCD) | 1-Amino-cyclopentane-1,3-dicarboxylic acid(cis-(1S,3S)-ACPD) | 1R,3R-ACPD | 1R,3S-ACPD | 1S, 3R-ACPD | CHEMBL29726 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H11NO4 |
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| Mol. Mass. | 173.1665 |
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| SMILES | N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O |
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| Structure | 
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