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TargetCathepsin G
LigandBDBM50279771
Substrate/Competitorn/a
Meas. Tech.ChEMBL_45530
pH7.5±n/a
Ki>15000±n/a nM
Commentsextracted
Citation Regan JMcGarry DBruno JGreen DNewman JHsu CYKline JBarton JTravis JChoi YMVolz FPauls HHarrison RZilberstein ABen-Sasson SAChang M Anionic- and lipophilic-mediated surface binding inhibitors of human leukocyte elastase. J Med Chem 40:3408-22 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cathepsin G
Name:Cathepsin G
Synonyms:CG
Type:PROTEIN
Mol. Mass.:28860.08
Organism:Homo sapiens (Human)
Description:ChEMBL_1469016
Residue:255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
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BDBM50279771
n/a
NameBDBM50279771
Synonyms:CHEMBL217744 | [4-Benzyloxy-5-{5-benzyloxy-4-[5-benzyloxy-2-carboxymethoxy-4-(2-carboxymethoxy-5-hydroxy-benzyl)-benzyl]-2-carboxymethoxy-benzyl}-2-(2-benzyloxy-5-carboxymethoxy-4-hydroxymethyl-benzyl)-phenoxy]-acetic acid
TypeSmall organic molecule
Emp. Form.C73H66O21
Mol. Mass.1279.2925
SMILESOCc1cc(OCc2ccccc2)c(Cc2cc(OCc3ccccc3)c(Cc3cc(OCc4ccccc4)c(Cc4cc(OCc5ccccc5)c(Cc5cc(O)ccc5OCC(O)=O)cc4OCC(O)=O)cc3OCC(O)=O)cc2OCC(O)=O)cc1OCC(O)=O
Structure
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