| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM50060964 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34330 (CHEMBL648113) |
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| Ki | 0.61±n/a nM |
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| Citation |  Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e] isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]pyrimidine-2,4 (1H,3H)-dione (A-131701): a uroselective alpha 1A adrenoceptor antagonist for the symptomatic treatment of benign pr J Med Chem40:3141-3 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 56862.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35368 |
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| Residue: | 520 |
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| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
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| BDBM50060964 |
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| n/a |
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| Name | BDBM50060964 |
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| Synonyms: | (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide | 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide | 5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide | CHEMBL836 | TAMSULOSIN |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28N2O5S |
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| Mol. Mass. | 408.512 |
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| SMILES | CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O |
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| Structure | 
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