| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50061329 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60661 (CHEMBL671698) |
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| Ki | 0.8±n/a nM |
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| Citation |  Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD (Aryloxy)alkylamines as selective human dopamine D4 receptor antagonists: potential antipsychotic agents. J Med Chem40:4026-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50061329 |
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| n/a |
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| Name | BDBM50061329 |
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| Synonyms: | (3-Phenylsulfanyl-propyl)-(2-p-tolyloxy-ethyl)-amine | CHEMBL130402 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23NOS |
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| Mol. Mass. | 301.446 |
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| SMILES | Cc1ccc(OCCNCCCSc2ccccc2)cc1 |
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| Structure | 
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