| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50061412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159973 (CHEMBL768120) |
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| Ki | 0.038±n/a nM |
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| Citation |  Wilkerson, WW; Dax, S; Cheatham, WW Nonsymmetrically substituted cyclic urea HIV protease inhibitors. J Med Chem40:4079-88 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50061412 |
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| n/a |
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| Name | BDBM50061412 |
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| Synonyms: | 3-[(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-3-(3-methoxy-benzyl)-2-oxo-[1,3]diazepan-1-ylmethyl]-N-pyrazin-2-yl-benzamide | CHEMBL131508 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H39N5O5 |
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| Mol. Mass. | 657.7575 |
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| SMILES | COc1cccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3cccc(c3)C(=O)Nc3cnccn3)C2=O)c1 |
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| Structure | 
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