| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Genome polyprotein |
|---|
| Ligand | BDBM50061526 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_158975 (CHEMBL763742) |
|---|
| IC50 | 1800±n/a nM |
|---|
| Citation |  Ogilvie, W; Bailey, M; Poupart, MA; Abraham, A; Bhavsar, A; Bonneau, P; Bordeleau, J; Bousquet, Y; Chabot, C; Duceppe, JS; Fazal, G; Goulet, S; Grand-Maître, C; Guse, I; Halmos, T; Lavallée, P; Leach, M; Malenfant, E; O'Meara, J; Plante, R; Plouffe, C; Poirier, M; Soucy, F; Yoakim, C; Déziel, R Peptidomimetic inhibitors of the human cytomegalovirus protease. J Med Chem40:4113-35 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Genome polyprotein |
|---|
| Name: | Genome polyprotein |
|---|
| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44361.04 |
|---|
| Organism: | Human rhinovirus B |
|---|
| Description: | ChEMBL_158953 |
|---|
| Residue: | 401 |
|---|
| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
|
|
|
|---|
| BDBM50061526 |
|---|
| n/a |
|---|
| Name | BDBM50061526 |
|---|
| Synonyms: | (S)-2-{(S)-2-[(S)-2-(2-Acetylamino-acetylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-N*1*-(3,3,3-trifluoro-1-methyl-2-oxo-propyl)-succinamide | CHEMBL133187 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H35F3N6O7 |
|---|
| Mol. Mass. | 552.5445 |
|---|
| SMILES | CC(C)[C@H](NC(=O)CNC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)NC(C)C(=O)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
