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TargetHuman rhinovirus A protease
LigandBDBM50061503
Substrate/Competitorn/a
Meas. Tech.ChEMBL_158975
IC50 200±n/a nM
Citation Ogilvie WBailey MPoupart MAAbraham ABhavsar ABonneau PBordeleau JBousquet YChabot CDuceppe JSFazal GGoulet SGrand-Maître CGuse IHalmos TLavallée PLeach MMalenfant EO'Meara JPlante RPlouffe CPoirier MSoucy FYoakim CDéziel R Peptidomimetic inhibitors of the human cytomegalovirus protease. J Med Chem 40:4113-35 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human rhinovirus A protease
Name:Human rhinovirus A protease
Synonyms:Human rhinovirus B 3A protease
Type:PROTEIN
Mol. Mass.:44361.04
Organism:Human rhinovirus B
Description:ChEMBL_158953
Residue:401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50061503
n/a
NameBDBM50061503
Synonyms:(S)-N*1*-(2-Benzylcarbamoyl-1-methyl-2-oxo-ethyl)-2-[(S)-2-(3,3-dimethyl-butyrylamino)-3,3-dimethyl-butyrylamino]-N*4*,N*4*-dimethyl-succinamide | CHEMBL422440
TypeSmall organic molecule
Emp. Form.C29H45N5O6
Mol. Mass.559.6975
SMILESCC(NC(=O)[C@H](CC(=O)N(C)C)NC(=O)[C@@H](NC(=O)CC(C)(C)C)C(C)(C)C)C(=O)C(=O)NCc1ccccc1
Structure
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