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TargetChymotrypsinogen A
LigandBDBM50061509
Substrate/Competitorn/a
Meas. Tech.ChEMBL_33820 (CHEMBL646850)
IC50>300000±n/a nM
Citation Ogilvie, WBailey, MPoupart, MAAbraham, ABhavsar, ABonneau, PBordeleau, JBousquet, YChabot, CDuceppe, JSFazal, GGoulet, SGrand-Maître, CGuse, IHalmos, TLavallée, PLeach, MMalenfant, EO'Meara, JPlante, RPlouffe, CPoirier, MSoucy, FYoakim, CDéziel, R Peptidomimetic inhibitors of the human cytomegalovirus protease. J Med Chem40:4113-35 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chymotrypsinogen A
Name:Chymotrypsinogen A
Synonyms:Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:Serine protease
Mol. Mass.:25670.88
Organism:Bos taurus (bovine)
Description:n/a
Residue:245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV
TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA
VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM
ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ
TLAAN
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  Blast E-value cutoff:
BDBM50061509
n/a
NameBDBM50061509
Synonyms:(S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimethyl-butyrylamino]-N*4*,N*4*-dimethyl-N*1*-[1-methyl-2-(5-methyl-benzooxazol-2-yl)-2-oxo-ethyl]-succinamide | CHEMBL133854
TypeSmall organic molecule
Emp. Form.C29H43N5O6
Mol. Mass.557.6816
SMILESCC(NC(=O)[C@H](CC(=O)N(C)C)NC(=O)[C@@H](NC(=O)CC(C)(C)C)C(C)(C)C)C(=O)c1nc2cc(C)ccc2o1
Structure
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