| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM50061569 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105269 (CHEMBL713141) |
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| Ki | 1.6±n/a nM |
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| Citation |  Witt-Enderby, PA; Chu, GH; Gillen, ML; Li, PK Development of a high-affinity ligand that binds irreversibly to Mel1b melatonin receptors. J Med Chem40:4195-8 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50061569 |
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| n/a |
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| Name | BDBM50061569 |
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| Synonyms: | CHEMBL131919 | Chloro-acetic acid 7-methoxy-1-(2-propionylamino-ethyl)-naphthalen-2-yl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20ClNO4 |
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| Mol. Mass. | 349.809 |
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| SMILES | CCC(=O)NCCc1c(OC(=O)CCl)ccc2ccc(OC)cc12 |
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| Structure | 
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