| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50061570 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105104 (CHEMBL715948) |
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| Ki | 1.3±n/a nM |
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| Citation |  Witt-Enderby, PA; Chu, GH; Gillen, ML; Li, PK Development of a high-affinity ligand that binds irreversibly to Mel1b melatonin receptors. J Med Chem40:4195-8 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50061570 |
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| n/a |
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| Name | BDBM50061570 |
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| Synonyms: | Bromo-acetic acid 7-methoxy-1-(2-propionylamino-ethyl)-naphthalen-2-yl ester | CHEMBL134416 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20BrNO4 |
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| Mol. Mass. | 394.26 |
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| SMILES | CCC(=O)NCCc1c(OC(=O)CBr)ccc2ccc(OC)cc12 |
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| Structure | 
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