| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM50062024 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48799 (CHEMBL662825) |
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| Ki | 192±n/a nM |
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| Citation |  Maduskuie, TP; McNamara, KJ; Ru, Y; Knabb, RM; Stouten, PF Rational design and synthesis of novel, potent bis-phenylamidine carboxylate factor Xa inhibitors. J Med Chem41:53-62 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | F10 | FA10_HUMAN | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor |
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| Type: | Enzyme |
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| Mol. Mass.: | 54726.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 488 |
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| Sequence: | MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
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| BDBM50062024 |
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| n/a |
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| Name | BDBM50062024 |
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| Synonyms: | 5-(4-Carbamimidoyl-phenyl)-3-(3-carbamimidoyl-phenyl)-pentanoic acid isopropyl ester | CHEMBL439642 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N4O2 |
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| Mol. Mass. | 380.4833 |
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| SMILES | CC(C)OC(=O)CC(CCc1ccc(cc1)C(N)=N)c1cccc(c1)C(N)=N |
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| Structure | 
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