| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50062058 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158347 (CHEMBL768491) |
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| Ki | 1.2±n/a nM |
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| Citation |  Curtin, ML; Davidsen, SK; Heyman, HR; Garland, RB; Sheppard, GS; Florjancic, AS; Xu, L; Carrera, GM; Steinman, DH; Trautmann, JA; Albert, DH; Magoc, TJ; Tapang, P; Rhein, DA; Conway, RG; Luo, G; Denissen, JF; Marsh, KC; Morgan, DW; Summers, JB Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists. J Med Chem41:74-95 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50062058 |
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| n/a |
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| Name | BDBM50062058 |
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| Synonyms: | 6-(4-Fluoro-phenyl)-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-piperazine-1-sulfonyl]-indole-1-carboxylic acid dimethylamide | CHEMBL174668 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H30FN7O3S |
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| Mol. Mass. | 575.657 |
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| SMILES | CN(C)C(=O)n1cc(c2ccc(cc12)-c1ccc(F)cc1)S(=O)(=O)N1CCN(Cn2c(C)nc3cnccc23)CC1 |
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| Structure | 
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