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TargetPlatelet activating factor receptor
LigandBDBM50062093
Substrate/Competitorn/a
Meas. Tech.ChEMBL_158347
Ki 2.2±n/a nM
Citation Curtin MLDavidsen SKHeyman HRGarland RBSheppard GSFlorjancic ASXu LCarrera GMSteinman DHTrautmann JAAlbert DHMagoc TJTapang PRhein DAConway RGLuo GDenissen JFMarsh KCMorgan DWSummers JB Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists. J Med Chem 41:74-95 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50062093
n/a
NameBDBM50062093
Synonyms:(4-Ethynyl-1H-indol-3-yl)-[3-fluoro-4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-phenyl]-methanone | CHEMBL174859
TypeSmall organic molecule
Emp. Form.C25H17FN4O
Mol. Mass.408.4271
SMILESCc1nc2cnccc2n1Cc1ccc(cc1F)C(=O)c1c[nH]c2cccc(C#C)c12
Structure
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