| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet activating factor receptor |
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| Ligand | BDBM50062091 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158347 |
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| Ki | 1.1±n/a nM |
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| Citation |  Curtin ML; Davidsen SK; Heyman HR; Garland RB; Sheppard GS; Florjancic AS; Xu L; Carrera GM; Steinman DH; Trautmann JA; Albert DH; Magoc TJ; Tapang P; Rhein DA; Conway RG; Luo G; Denissen JF; Marsh KC; Morgan DW; Summers JB Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists. J Med Chem 41:74-95 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet activating factor receptor |
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| Name: | Platelet activating factor receptor |
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| Synonyms: | PAF-R | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50062091 |
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| n/a |
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| Name | BDBM50062091 |
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| Synonyms: | 1-(2-Ethoxy-ethyl)-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-benzoyl]-1H-indole-4-carboxylic acid methyl ester | CHEMBL173586 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H28N4O4 |
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| Mol. Mass. | 496.557 |
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| SMILES | CCOCCn1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(=O)OC |
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| Structure | 
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