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TargetPlatelet-activating factor receptor
LigandBDBM50062064
Substrate/Competitorn/a
Meas. Tech.ChEMBL_158347 (CHEMBL768491)
Ki 0.860000±n/a nM
Citation Curtin, MLDavidsen, SKHeyman, HRGarland, RBSheppard, GSFlorjancic, ASXu, LCarrera, GMSteinman, DHTrautmann, JAAlbert, DHMagoc, TJTapang, PRhein, DAConway, RGLuo, GDenissen, JFMarsh, KCMorgan, DWSummers, JB Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists. J Med Chem41:74-95 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Platelet-activating factor receptor
Name:Platelet-activating factor receptor
Synonyms:PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50062064
n/a
NameBDBM50062064
Synonyms:1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-benzoyl]-1H-indole-4-carboxylic acid benzyl ester | CHEMBL427307
TypeSmall organic molecule
Emp. Form.C34H29N5O4
Mol. Mass.571.6252
SMILESCN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(=O)OCc1ccccc1
Structure
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