| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50062858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29122 (CHEMBL642256) |
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| Ki | 0.094±n/a nM |
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| Citation |  Holschbach, MH; Fein, T; Krummeich, C; Lewis, RG; Wutz, W; Schwabe, U; Unterlugauer, D; Olsson, RA A1 adenosine receptor antagonists as ligands for positron emission tomography (PET) and single-photon emission tomography (SPET). J Med Chem41:555-63 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50062858 |
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| n/a |
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| Name | BDBM50062858 |
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| Synonyms: | 8-Cyclopentyl-3-(2-fluoro-propyl)-1-propyl-3,7-dihydro-purine-2,6-dione | CHEMBL152026 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H23FN4O2 |
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| Mol. Mass. | 322.3778 |
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| SMILES | CCCn1c(=O)n(CC(C)F)c2nc([nH]c2c1=O)C1CCCC1 |
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| Structure | 
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