| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50036764 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34029 (CHEMBL646168) |
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| Ki | >10000±n/a nM |
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| Citation |  Quaglia, W; Giannella, M; Piergentili, A; Pigini, M; Brasili, L; Di Toro, R; Rossetti, L; Spampinato, S; Melchiorre, C 1'-Benzyl-3,4-dihydrospiro[2H-1- benzothiopyran-2,4'-piperidine] (spipethiane), a potent and highly selective sigma1 ligand. J Med Chem41:1557-60 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A |
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| Type: | Protein |
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| Mol. Mass.: | 51620.15 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P43140 |
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| Residue: | 466 |
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| Sequence: | MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
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| BDBM50036764 |
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| n/a |
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| Name | BDBM50036764 |
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| Synonyms: | 1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-2,4'-(hexahydropyridine)]-1-one; hydrochloride | CHEMBL41830 | CHEMBL554874 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23NO |
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| Mol. Mass. | 305.4134 |
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| SMILES | O=C1c2ccccc2CCC11CCN(Cc2ccccc2)CC1 |
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| Structure | 
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