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TargetGag-Pol polyprotein [489-587]
LigandBDBM50064198
Substrate/Competitorn/a
Meas. Tech.ChEMBL_158768 (CHEMBL772929)
Ki 80±n/a nM
Citation Martin, SFDorsey, GOGane, THillier, MCKessler, HBaur, MMathä, BErickson, JWBhat, TNMunshi, SGulnik, SVTopol, IA Cyclopropane-derived peptidomimetics. Design, synthesis, evaluation, and structure of novel HIV-1 protease inhibitors. J Med Chem41:1581-97 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50064198
n/a
NameBDBM50064198
Synonyms:1N-{1-benzyl-4-[2,2-dimethyl-3-methyl(2-pyridylmethyl)carbamoylcyclopropylcarboxamido]-2,3-dihydroxy-5-phenylpentyl}-2N,3,3-trimethyl-2N-(2-pyridylmethyl)-1,2-cyclopropanedicarboxamide | CHEMBL290847
TypeSmall organic molecule
Emp. Form.C46H56N6O6
Mol. Mass.788.9734
SMILESCN(Cc1ccccn1)C(=O)[C@H]1[C@H](C(=O)N[C@@H](Cc2ccccc2)[C@@H](O)[C@H](O)[C@H](Cc2ccccc2)NC(=O)[C@H]2[C@H](C(=O)N(C)Cc3ccccn3)C2(C)C)C1(C)C
Structure
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