| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor gamma |
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| Ligand | BDBM50064250 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_196165 (CHEMBL804938) |
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| IC50 | 55±n/a nM |
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| Citation |  Muccio, DD; Brouillette, WJ; Breitman, TR; Taimi, M; Emanuel, PD; Zhang, X; Chen, G; Sani, BP; Venepally, P; Reddy, L; Alam, M; Simpson-Herren, L; Hill, DL Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias. J Med Chem41:1679-87 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor gamma |
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| Name: | Retinoic acid receptor gamma |
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| Synonyms: | Nr1b3 | RARG_MOUSE | Rarg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50896.02 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_196161 |
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| Residue: | 458 |
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| Sequence: | MATNKERLFAPGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSKPGPHPKASSEDEAPGGQGKRGQSPQPDQGP
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| BDBM50064250 |
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| n/a |
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| Name | BDBM50064250 |
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| Synonyms: | (2E,4E,6E)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid | 3,7-dimethyl-8-(1,2,3,4-tetrahydro-1-naphthalenyliden)-(2E,4E,6E)-2,4,6-octatrienoic acid | CHEMBL46397 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22O2 |
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| Mol. Mass. | 294.3875 |
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| SMILES | C\C(\C=C\C=C(/C)\C=C1/CCCc2ccccc12)=C/C(O)=O |
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| Structure | 
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