| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
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| Ligand | BDBM31883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195641 (CHEMBL795959) |
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| IC50 | 5±n/a nM |
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| Citation |  Muccio, DD; Brouillette, WJ; Breitman, TR; Taimi, M; Emanuel, PD; Zhang, X; Chen, G; Sani, BP; Venepally, P; Reddy, L; Alam, M; Simpson-Herren, L; Hill, DL Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias. J Med Chem41:1679-87 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor beta |
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| Name: | Retinoic acid receptor beta |
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| Synonyms: | Nr1b2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RARB_MOUSE | Rarb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53344.93 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_195641 |
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| Residue: | 482 |
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| Sequence: | MSTSSHACPVPAVRGHMTHYPAAPYPLLFPPVIRGLSLPPLHGLHGHPPPSGCSTPSPAS
VGQACQRTTGGSQFAASTKWTPSLNAAIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQD
KSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGM
SKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSS
ADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRI
CTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAIC
LICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAE
RVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNIAEHSPSVSPSSVENSGVSQSPL
LQ
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| BDBM31883 |
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| n/a |
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| Name | BDBM31883 |
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| Synonyms: | 9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC ACID | AT-RA | Atralin | CHEMBL38 | MLS000028588 | SMR000058245 | TRETINOIN | Vitamin A acid | [3H]RA | [3H]Retinoic acid | [3H]Vitamin A acid | [3H]tretinoin | all-trans retinoic acid | cid_444795 |
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| Type | radiolabeled ligand |
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| Emp. Form. | C20H28O2 |
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| Mol. Mass. | 300.4351 |
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| SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O |c:4| |
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| Structure | 
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