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TargetGag-Pol polyprotein [489-587]
LigandBDBM50064593
Substrate/Competitorn/a
Meas. Tech.ChEMBL_157717 (CHEMBL763391)
Ki 0.052±n/a nM
Citation Han, QChang, CHLi, RRu, YJadhav, PKLam, PY Cyclic HIV protease inhibitors: design and synthesis of orally bioavailable, pyrazole P2/P2' cyclic ureas with improved potency. J Med Chem41:2019-28 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50064593
n/a
NameBDBM50064593
Synonyms:3-{(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-2-oxo-3-[3-(2H-pyrazol-3-yl)-benzyl]-[1,3]diazepan-1-ylmethyl}-N-(2-morpholin-4-yl-ethyl)-benzamide | CHEMBL304713
TypeSmall organic molecule
Emp. Form.C43H48N6O5
Mol. Mass.728.8784
SMILESO[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2cccc(c2)-c2cc[nH]n2)C(=O)N(Cc2cccc(c2)C(=O)NCCN2CCOCC2)[C@@H]1Cc1ccccc1
Structure
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