| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50064981 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_200965 (CHEMBL802053) |
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| Ki | 0.87±n/a nM |
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| Citation |  Huang, Y; Hammond, PS; Whirrett, BR; Kuhner, RJ; Wu, L; Childers, SR; Mach, RH Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands. J Med Chem41:2361-70 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50064981 |
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| n/a |
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| Name | BDBM50064981 |
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| Synonyms: | CHEMBL77405 | N-(1-Benzyl-piperidin-4-yl)-2-(3-bromo-phenyl)-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23BrN2O |
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| Mol. Mass. | 387.313 |
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| SMILES | Brc1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 |
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| Structure | 
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