| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50065144 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200969 (CHEMBL802057) |
|---|
| Ki | 0.63±n/a nM |
|---|
| Citation |  John, CS; Lim, BB; Vilner, BJ; Geyer, BC; Bowen, WD Substituted halogenated arylsulfonamides: a new class of sigma receptor binding tumor imaging agents. J Med Chem41:2445-50 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25124.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99720 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM50065144 |
|---|
| n/a |
|---|
| Name | BDBM50065144 |
|---|
| Synonyms: | CHEMBL79660 | N-(2-Azepan-1-yl-ethyl)-4-bromo-benzenesulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H21BrN2O2S |
|---|
| Mol. Mass. | 361.298 |
|---|
| SMILES | Brc1ccc(cc1)S(=O)(=O)NCCN1CCCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
