| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50065469 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143830 (CHEMBL748714) |
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| Ki | 4.6±n/a nM |
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| Citation |  Zarrinmayeh, H; Nunes, AM; Ornstein, PL; Zimmerman, DM; Arnold, MB; Schober, DA; Gackenheimer, SL; Bruns, RF; Hipskind, PA; Britton, TC; Cantrell, BE; Gehlert, DR Synthesis and evaluation of a series of novel 2-[(4-chlorophenoxy)methyl]benzimidazoles as selective neuropeptide Y Y1 receptor antagonists. J Med Chem41:2709-19 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50065469 |
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| n/a |
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| Name | BDBM50065469 |
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| Synonyms: | 2-Diphenylacetylamino-5-guanidino-pentanoic acid 4-hydroxy-benzylamide | CHEMBL44246 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H31N5O3 |
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| Mol. Mass. | 473.5667 |
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| SMILES | NC(=N)NCCCC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |
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| Structure | 
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