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TargetGenome polyprotein
LigandBDBM50065595
Substrate/Competitorn/a
Meas. Tech.ChEMBL_160898 (CHEMBL771794)
Ki 10±n/a nM
Citation Webber, SEOkano, KLittle, TLReich, SHXin, YFuhrman, SAMatthews, DALove, RAHendrickson, TFPatick, AKMeador, JWFerre, RABrown, ELFord, CEBinford, SLWorland, ST Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements. J Med Chem41:2786-805 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Genome polyprotein
Name:Genome polyprotein
Synonyms:Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:PROTEIN
Mol. Mass.:44361.04
Organism:Human rhinovirus B
Description:ChEMBL_158953
Residue:401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50065595
n/a
NameBDBM50065595
Synonyms:((S)-1-{(S)-1-[(S)-2-(3,3-Dimethyl-ureido)-1-formyl-ethylcarbamoyl]-2-phenyl-ethylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester | CHEMBL97601
TypeSmall organic molecule
Emp. Form.C29H39N5O6
Mol. Mass.553.6499
SMILESCC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CNC(=O)N(C)C)C=O
Structure
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