| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50065775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29303 (CHEMBL640364) |
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| Ki | 6.99±n/a nM |
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| Citation |  Kim, YC; de Zwart, M; Chang, L; Moro, S; von Frijtag Drabbe Künzel, JK; Melman, N; IJzerman, AP; Jacobson, KA Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having high potency at the human A2B and A3 receptor subtypes. J Med Chem41:2835-45 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50065775 |
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| n/a |
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| Name | BDBM50065775 |
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| Synonyms: | 5-Amino-pentanoic acid (9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-amide | CHEMBL97700 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClN6O2 |
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| Mol. Mass. | 384.82 |
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| SMILES | NCCCCC(=O)Nc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccco1 |
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| Structure | 
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