| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50065758 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30000 (CHEMBL643011) |
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| Ki | 3.64±n/a nM |
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| Citation |  Kim, YC; de Zwart, M; Chang, L; Moro, S; von Frijtag Drabbe Künzel, JK; Melman, N; IJzerman, AP; Jacobson, KA Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having high potency at the human A2B and A3 receptor subtypes. J Med Chem41:2835-45 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 45015.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat A2A receptors expressed in CHO cells. |
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| Residue: | 410 |
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| Sequence: | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
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| BDBM50065758 |
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| n/a |
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| Name | BDBM50065758 |
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| Synonyms: | CHEMBL98570 | [4-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-butyl]-carbamic acid tert-butyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN6O4 |
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| Mol. Mass. | 484.935 |
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| SMILES | CC(C)(C)OC(=O)NCCCCC(=O)Nc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccco1 |
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| Structure | 
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