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TargetChymotrypsinogen A
LigandBDBM50066337
Substrate/Competitorn/a
Meas. Tech.ChEMBL_49754 (CHEMBL662086)
Ki>50000±n/a nM
Citation Tucker, TJBrady, SFLumma, WCLewis, SDGardell, SJNaylor-Olsen, AMYan, YSisko, JTStauffer, KJLucas, BJLynch, JJCook, JJStranieri, MTHolahan, MALyle, EABaskin, EPChen, IWDancheck, KBKrueger, JACooper, CMVacca, JP Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position. J Med Chem41:3210-9 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chymotrypsinogen A
Name:Chymotrypsinogen A
Synonyms:Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:Serine protease
Mol. Mass.:25670.88
Organism:Bos taurus (bovine)
Description:n/a
Residue:245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV
TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA
VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM
ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ
TLAAN
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  Blast E-value cutoff:
BDBM50066337
n/a
NameBDBM50066337
Synonyms:(S)-1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dichloro-benzylamide | CHEMBL108183
TypeSmall organic molecule
Emp. Form.C27H27Cl2N3O2
Mol. Mass.496.428
SMILESNC(C(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1Cl
Structure
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